sertraline weight gain. It has been shown that taking Zoloft (sertraline) for an extended period of time (six months to a year) may cause a slight increase in weight (by 1% to 1.6%). An individual weighing 150 pounds (68 kilograms) would gain an extra 0.7 to 1.1 kilograms (1.5 to 2.4 pounds). The majority of patients using Zoloft do so for an extended period of time, although even with shorter courses of medication, individuals rarely experience significant weight gain.
There have been reports of Zoloft-induced weight loss in children, which may be attributable to the drug’s gastrointestinal adverse effects. At least 2% of 281 Zoloft-treated children reported weight loss, which was twice as high as the placebo group (an inactive pill).
Indications for the SSRI Zoloft include treating depression, anxiety, and bulimia.
Depression
Insanity from compulsions and rituals
Condition characterized by frequent and severe feelings of panic
Difficulty Recovering From Stress After a Traumatic Event
Condition characterized by excessive worry about interactions with others
Mood swings before menstruation
Does Zoloft cause significantly more weight gain than other SSRIs?
Sertraline (Zoloft) and fluoxetine (Prozac) tend to be the SSRIs that induce the least amount of weight gain.
Variable weight gain has been associated with SSRI use. Gaining weight is typically scored as high as
fluoxetine (Prozac) lowest; sertraline (Zoloft); citalopram (Celexa); escitalopram (Lexapro); fluvoxamine (Luvox) highest; paroxetine (Paxil) highest (Paxil).
Long-term treatment with fluoxetine (Prozac), sertraline (Zoloft), or paroxetine was compared in a randomized, double-blind research involving 284 patients with major depressive disorder (Paxil).
Patients taking paroxetine gained much more weight than those on the other two SSRIs, sertraline and fluoxetine, whereas patients taking fluoxetine lost weight slightly more than those taking the other two.
Patients who were given paroxetine were more likely to experience a weight gain of 7% or more from the study’s beginning compared to patients who were given fluoxetine or sertraline.
Citalopram, fluoxetine, fluvoxamine, paroxetine, or sertraline) and the tricyclic antidepressant (TCA) clomipramine were evaluated for their effects on weight gain in a 2.5-year open-label trial involving 138 individuals being treated for obsessive-compulsive disorder (OCD).
There was notable weight increase in all groups except those on fluoxetine. The most significant weight increase was seen with the use of clomipramine (a TCA). The risk of weight gain while taking a TCA is well-documented, and it is known that these drugs are far worse than SSRIs.
Weight gain was least common with SSRIs fluoxetine (Prozac) and sertraline (Zoloft).
Similar to Prozac and Zoloft, the percentage of people who
